Award Notices

July 2015

Maryland Innovation Initiative Funded Projects

These Maryland Innovation Initiative awards were given through the Innovation Commercialization Program, which provides funding to support the commercialization of qualified university technologies at three distinct stages: pre-commercial translational research (Phase I), commercialization planning (Phase II) and early-stage product development (Phase III).


Anacrusis, Inc.
- Developing an App called “Read Ahead” for Sight-Reading at the piano. Licensed technology from Johns Hopkins University.

Analytical Informatics
- Creating a suite of software based tools designed to improve quality and efficiency in health care. Licensed technology from University of Maryland Baltimore.

Aqua Animal Health
- Developing a Myostatin inhibitor for aquaculture which will improve feeding efficiency, accelerate growth, increase filet size, and increase fry (newly hatched fish) and fingerling survival rates. Licensed technology from Johns Hopkins University in collaboration with University of Maryland, Baltimore.

AsclepiX Therapeutics
- Developing a novel biomimetic peptide for the treatment of Macular Edema. Licensed technology from Johns Hopkins University.

Biomecite Diagnostics, LLC
- Developing a microbiome diagnostic for inflammatory bowel disease. Licensed technology from University of Maryland, Baltimore

CardioSolv Ablation Technologies, Inc.
- Developing software validation for regulatory compliance in simulation-guided ablation. Licensed technology from Johns Hopkins University

Diagnostic anSERS Inc.
- Creating ink-jet printed sensors for authentication and trace containment detection. Licensed technology from University of Maryland, College Park.

emocha Mobile Health, Inc.
- Provides the mobile tools to engage and manage the patient and their safety. Licensed technology from Johns Hopkins University.

Glycomantra, Inc..
- Developing a galectin-3 antagonist for prostate cancer therapy.

Grip Boost, LLC.
- Developing a product that can restore old football gloves to ‘like-new’ tack without leaving residue on the ball. Licensed technology from University of Maryland, College Park.

Harpoon Medical
- Developing a minimally invasive surgical tool that surgeons can use to access the mitral valve in a beating heart, under image guidance via a small incision between the ribs, and repair it. Licensed technology from University of Maryland, Baltimore.

JPLC Associates
- Creating a unifying device for mechanical and dosimetric quality assurance measurements in radiation therapy. Licensed technology from Johns Hopkins University.

MedSense, LLC
- Developing a sensor made with biocompatible materials, is smaller, superior performance, and lower product costs than currently available. Licensed technology from University of Maryland, College Park.

MF Fire Benefic, LLC
- Producing a Mulciber Stove – an atuomated, ultra-clean wood stone. Licensed technology from University of Maryland, College Park.

MycoMed Technologies, LLC
- Developing a diagnostic test for detection of aspergillus infection and invasive aspergillosis. Licensed technology from Johns Hopkins University.

N5 Sensors
- Developing an ultra-low profile, low-power, and smart sensor architecture for monitoring a variety of trace gases (toxic, explosive, corrosive) in air. Licensed technology from University of Maryland, College Park.

- Working on the treatment of Otitis Media without puncturing the ear drum. Licensed technology from University of Maryland, College Park.

React Labs
- Real-time polling platform. Licensed technology from University of Maryland, College Park.

respeQ, Inc.
- Developing a suite of products that uniquely monitor in-home respiratory function that initially relate to sleep disordered breathing and wirelessly transmit those outputs to a mobile diagnostic application platform. Licensed technology from Johns Hopkins University.

Revolve Biotechnologies, Inc
- Developing high-quality DNA mutant libraries for engineering high-value proteins. Licensed technology from Johns Hopkins University.

Second Write
- Creating a method for source code recovery. Licensed technology from University of Maryland, College Park.

SilcsBio LLC
- Developing advanced molecular modeling software that enhances drug discovery. Licensed technology from University of Maryland, Baltimore.

SONAVEX Surgical
- Developing an ultrasound-based vascular monitoring system. Licensed technology from Johns Hopkins University


Johns Hopkins University
- Developing bifunctional immunostimulatory antibodies for treatment of cancer (Bedi)
- Develop REMS: Robotic ENT Microsurgery System (Balicki)
- Develop codeDNA: Advanced Malware Variant Detection (Breiner)
- Developing a Papillomavirus-like Particles (VLP) as Broad Spectrum Human Papillomavirus (HPV) Vaccines (Roden)
- Developing biodegradable aAPC particles for cancer immunotherapy (Green)
- Developing a drug to reverse atherosclerotic heart disease in diabetic mice (Chatterjee)
- Develop an adaptive robotic platform for expandable, easy to program collaborative industrial robots (Hager)
- Developing a saliva based rapid diagnostic test for detection of asymptomatic carriers of the malaria parasite (Dinglasan0
- Develop and commercialize a novel system, RestEaze that can distinguish GLMS movements (leg movements) from PLMS movements (foot flexions)(Allen)
- Improve delivery, enhance efficacy, and prolong glutaminase inhibitor drug levels in the tumor with the ultimate goal of improving outcomes for pancreatic cancer patients (Le)
- Developing LiFi enabled 3D Optical Imaging for collision safety and autonomous transportation (Torruellas)
- Improving computer-assisted craniomaxillofacial surgery (Gordon)
- Developing novel microfuidic technology to revolutionize forensic analysis of multiple contributor DNA samples (Feldman)
- Using cell permeable peptides derived from Pirt2 mutant protein to treat chronic pain (Dong)
- Developing a small molecule PSMA inhibitor to treat Inflammatory Bowel Disease. (Slusher)
- Developing a device that will reduce reoperation rates in breast conserving surgery. (Benkoski)
- Developing a minimally invasive solution for the treatment of T2DM. (Pasricha)
- Developing a blood test based on methylated gene markers for breast cancer. (Sukumar)
- Developing an inexpensive tool, called FastStitch, to improve the surgical suture process. (Nguyen)
- Creating a device to assess cardiac filling pressure for preventing re-hospitalization for heart failure. (Silber)
- Introduced a diagnostic method for rapid detection of significant coronary heart disease. (McVeigh)
- Developing a cancer targeting agent, which has special relevance in castration-resistance prostate cancer (In collaboration with University of Maryland, Baltimore County). (Laiho)
- Developing a device to monitor blood vessel health in the immediate post-surgical period (In collaboration with University of Maryland Baltimore).
- Developing a method for purification of single-walled carbon Nanotubes. (Cammarata)
- Developing a device, called MouthLab, to enable the fast sampling of medical data. (Fridman)
- Developing a new lotion to augments wound healing, improves healing skin quality and reduces scar size. (Walston)
- Developing a polymeric fore sensor that is used with middle ear titanium prostheses to provide feedback to the surgeon. (Francis)
- Developing non-invasive quantitative CT imaging-based alternative that will provide accurate and rapid determination of the functional significance of coronary artery disease. (Lardo)
- Evaluating the efficacy and toxicity of artemisinin dimers in a mouse model and to select the lead   dimer for further development towards clinical studies in humans. (Boger)
- Develop a prototypic nanoparticle based system to mediate redirected lysis by human antigen-specific cytotoxic T lymphocytes, CTL, to tumor cells that would otherwise not be recognized. (Schneck)
- Developing a technology to use autologous volar fibroblasts to create new thick skin at the stump site for amputees. (Kang)
- Commercialize novel chemical exchange saturation transfer (CEST) magnetic resonance imaging  (MRI) biosensors. (van Zijl)
- Developing a downloadable software application to conduct patient “handoffs” to improve patient safety. (Goldberg)
- Developing a peptide-based therapy for acute and chronic diarrheal diseases. (Zachos)
- Developing a more effective treatment for seizures using amino acid therapy. (Hartman)
- Developing a low cost, high speed, wide dynamic range, software configurable, multimodel imaging sensor. (Rizk)

Morgan State University
- Developing a clean, efficient, and cost-effective biomass combustion system – CycloBurnTM (Lee)
- Developing the iCrystal System and new crystallization platforms for rapid drug treatment. (Aslan-Ph.2)
- Developing technology that offers a cost-effective and environmental friendly alternate to produce biofuel using naturally available sea water and the sun’s energy. (Sitther)

University of Maryland Baltimore
- Developing a new target and approach to antibiotic therapy (Wilks)
- Using magnetic nanoparticles for the treatment of dental disease (Masri)
- Developing VNLG-152 as a novel targeted therapy for triple negative breast cancer (Njar)
- Developing a technology for Alzheimer’s disease therapy that targets an inflammatory pathway in asymptomatic and symptomatic patients. (Zimmer)
- Develop a method to rapidly assess the function of NKT cells in cancer patients (Webb)
- Developing anti-thrombosis antibody product to improve clinic treatments (Xu)
- Creating a commercial development of a vaccine against Staphylococcus aureus. (Shirtliff)
- Developing a novel hybrid mesh for the treatment of pelvic organ prolapse. (ZSX Medical-Ph.2)
- Developing a technology, called RelaxDetect, which can detect biopharmaceutical aggregation via water relaxation in sealed vials. (Bruce Yu)
- Refining and validating the first universal cancer immunotherapy, At-CAR (Anti-tag Chimeric Antigen Receptor). (Davila)
- Develop a thermal endoscope for laparoscopy. This technique will reduce serious intraoperative complications by over 50%. (Pearl)
- Developing a lipid-based rapid, accurate and automatable method of pathogen detection in the clinic and mobile units when miniaturized. (Ernst)
- Commercialization of an Inflammatory Bowel Disease (IBD) diagnostic based on a microbiome signature technology. (ITVMD-Ph.2)
- Developing an interactive web-based software that will be commercialized for detecting and addressing parental psychosocial risk factors for child abuse/neglect within healthcare settings. (Dubowitz)
- Develop a unique opioid analgesic with reduced tolerance. (Coop)
- Design, manufacture and test pre-commercial Coaptive Ultrasound Gastrostomy (CUG) products for use in gastrostomy tube insertions. (Tropello)
- Developing a topical cream for treatment of cervical intraepithelial neoplasia. (Khanna)

University of Maryland Baltimore County
- Biomarker discovery and validation for Kinase Inhibitors (Bieberich)
- Developing a geared infinitely variable transmission with minimal speed fluctuation. (Zhu)
- Working to increase food safety and agricultural productivity through innovative feed additives. (MycoInnovation)
- Developing soluble CD80 (CD80-Fc) as a therapeutic agent for the treatment of cancer. (Ostrand-Rosenberg)
- Developing a turbulence-free CCD camera with nonclassical imaging resolution. (Shih)
- Develop and evaluate the efficacy of a recombinant NNV (Nervous necrosis virus) vaccine. (Vakharia)
- Produce a bioamended activated carbon pellet seeded with PCB- degrading microorganisms to reduce the concentration of polychlorinated biphenyls (PCBs) in sediments. (Sowers)
- Develop an alternative approach to detect attack patterns by investigating network flows to predict multi-step attacks better than any other system of its kind. (Karabatis)
- Developing a sensing system comprising of ultra-low cost textile-based nonrigid capacitive sensor arrays and inertial sensors that allow individuals with upper extremity paralysis to control their appliances and security systems remotely. (Banerjee)
- Developing an App for real-time audience enhancement and music education during music presentation and concerts. (Dusman)

University of Maryland College Park
- Developing an integrated power electronic charger/converter for plug-in electric vehicles. (Khaligh)
- Developing an efficient mucosal vaccination mediated by the Neonatal Fc Receptor. (Zhu)
- Creating hemostatic bandages based on a new biocompatible polymer (In collaboration with University of Maryland Baltimore). (Raghavan)
- Developing and testing protocols for scour sensing post deployment. (Tauros-Ph.2)
- Developing novel acyclic cucurbituril molecular containers as broad spectrum reversal agents for neuromuscular block agents used during surgery. (Isaacs)
- Developing a clinical assay that would provide a tool to improve time to diagnose and monitor disease progression in ALS and possibly other neuromuscular diseases (In collaboration with University of Maryland, Baltimore). (Chin)
- Developing a vaccine against a significant swine pathogen, procine reproductive and respiratory syndrome virus (PRRSV). (Zhang)
- Developing 2D hyperspectral imaging techniques for manufacturing yield and device failure analysis for photovoltaic cells and LEDs. (Bartolo)
- Develop a new technology for the production of liposomal nanoparticle drugs in a unique continuous-flow manufacturing process. (DeVoe)
- Develop data analysis tools on a user-friendly web interface and customize them for a variety of clients ranging from national chain restaurants to other establishments and local health departments in searching the existing nationwide food safety inspections database. (Bederson)
- Developing a novel, generalized approach to the formulation of vaccines against Gram-negative pathogens (In collaboration with University of Maryland, Baltimore). (DeShong)
- Customize Behavioral Activation Treatment for Depression (BATD) for a mobile platform to be used by clinicians and their patients by creating a BATD mobile application to be used in conjunction with therapy. (Lejeuz)
- Developing a non-invasive way to evaluate the quality of a donor kidney known as kidney viability assessment system (KVAS). (Chen)